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Self-powered patch monitors glucose levels during exercise

Self-powered patch monitors glucose levels during exercise

Source: http://www.mdpi.com/2072-666X/8/9/265/htm

Self-powered patch monitors glucose levels during exercise

A Single-Use, Self-Powered, Paper-Based Sensor Patch for Detection of Exercise-Induced Hypoglycemia
Eunyoung Cho, Maedeh Mohammadifar and Seokheun Choi *Orcid
Bioelectronics & Microsystems Laboratory, Department of Electrical & Computer Engineering, State University of New York-Binghamton, Binghamton, NY 13902, USA

Abstract:

Self-powered patch monitors glucose levels during exerciseWe report a paper-based self-powered sensor patch for prevention and management of exercise-induced hypoglycemia. The article describes the fabrication, in vitro, and in vivo characterization of the sensor for glucose monitoring in human sweat. This wearable, non-invasive, single-use biosensor integrates a vertically stacked, paper-based glucose/oxygen enzymatic fuel cell into a standard Band-Aid adhesive patch. The paper-based device attaches directly to skin, wicks sweat by using capillary forces to a reservoir where chemical energy is converted to electrical energy, and monitors glucose without external power and sophisticated readout instruments. The device utilizes (1) a 3-D paper-based fuel cell configuration, (2) an electrically conducting microfluidic reservoir for a high anode surface area and efficient mass transfer, and (3) a direct electron transfer between glucose oxidase and anodes for enhanced electron discharge properties. The developed sensor shows a high linearity of current at 0.02–1.0 mg/mL glucose centration (R2 = 0.989) with a high sensitivity of 1.35 µA/mM.
 

Keywords: sweat sensor patch; self-powered glucose sensor; enzymatic fuel cell; paper-based device; exercise-induced hypoglycemia

 

 

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